Sugi Predict

Sugi Predict / Compounds / SCHEMBL1449604

SCHEMBL1449604

SCHEMBL1449604

O=C(O)C(Br)CCCCC(Br)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 1/20 0.73
▸ PPARD Q03181 1/20 0.73
▸ ZDHHC20 Q5W0Z9 1/20 0.73
▸ ZDHHC2 Q9UIJ5 1/20 0.73
▸ ALDH1A1 P00352 3/20 0.55
▸ TSHR P16473 1/20 0.55
▸ THRB P10828 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ CYP2C19 P33261 1/20 0.42
▸ ZDHHC7 Q9NXF8 1/20 0.41
▸ GSR P00390 1/20 0.39
▸ GPR84 Q9NQS5 3/20 0.37
▸ RNPEP Q9H4A4 1/20 0.37
▸ FFAR1 O14842 1/20 0.37
▸ MAPT P10636 1/20 0.36
▸ ARG2 P78540 4/20 0.34
▸ ARG1 P05089 3/20 0.34
▸ CHRM1 P11229 1/20 0.33
▸ AKR1A1 P14550 1/20 0.33
▸ CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL689632 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL9621074 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL7658440 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL688574 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL22826569 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL689503 0.97 LCK (0.77) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL2122342 0.94 LCK (0.65) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL4414310 0.89 LCK (0.61) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL7971309 0.89 LCK (0.61) LCKPPARDZDHHC20ZDHHC2ALDH1A1
SCHEMBL26221398 0.89 LCK (0.61) LCKPPARDZDHHC20ZDHHC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102010507-A Method for preparing copolymer with multielement alternating structure UNIV ZHEJIANG 2011-04-13 — — CN claimed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 — — US disclosed
CN-102010507-A Method for preparing copolymer with multielement alternating structure UNIV ZHEJIANG 2011-04-13 — — CN disclosed
US-7910578-B2 8,10-diaza-bicyclo[4.3.1]decane derivatives and their medical use NEUROSEARCH A/S (DK) 2011-03-22 — — US disclosed
CN-1984981-B Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO 2010-11-17 — — CN disclosed
US-20090099153-A1 NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE ANIONA APS (DK) 2009-04-16 — — US disclosed
EP-2029607-A1 NOVEL 8,10-DIAZA-BICYCLOÝ4.3.1¨DECANE DERIVATIVES AND THEIR MEDICAL USE NeuroSearch A/S (DK) 2009-03-04 — — EP disclosed
CN-100430426-C Thermoplastic elastomer composition and molded article KANEGAFUCHI CHEMICAL IND (JP) 2008-11-05 — — CN disclosed
WO-2007135121-A1 NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE NEUROSEARCH A/S (DK) 2007-11-29 — — WO disclosed
CN-101016400-A Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-08-15 — — CN disclosed
CN-1315949-C Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-05-16 — — CN disclosed
CN-1914245-A Thermoplastic elastomer composition and molded article KANEGAFUCHI CHEMICAL IND (JP) 2007-02-14 — — CN disclosed
CN-1914244-A Thermoplastic elastomer composition and molded article KANEGAFUCHI CHEMICAL IND (JP) 2007-02-14 — — CN disclosed
US-7101630-B2 Diarylamino group-containing copolymer, organic electroluminescent device, and method of producing hole transport layer for organic electroluminescent device KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2006-09-05 — — US disclosed
US-20050008893-A1 Diarylamino group-containing copolymer, organic electroluminescent device, and method of producing hole transport layer for organic electroluminescent device KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2005-01-13 — — US disclosed
CN-1509318-A Thermoplastic resin composition ��Ԩ��ѧ��ҵ��ʽ���� 2004-06-30 — — CN disclosed
EP-0279978-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING ALPHA-HALOGENATED DICARBOXYLIC ACIDS Epis S.A. (CH) 1992-01-02 — — EP disclosed
US-4908385-A Pharmaceuticals EPIS S.A. (CH) 1990-03-13 — — US disclosed
EP-0279978-A1 Pharmaceutical compositions containing alpha-halogenated dicarboxylic acids Epis S.A. (CH) 1988-08-31 — — EP disclosed
WO-1988002746-A1 MEDICAMENTS CONTAINING ALPHA-HALOGENATED DICARBOXYLIC ACIDS EPIS S.A. (CH) 1988-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099153-A1 NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE CHRNA10, CHRNA7, CHRNA3 LCK 2675/4885PPARD 212/4885ZDHHC20 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.