Methionine Sulfoxide

Methionine Sulfoxide

SCHEMBL288041

C[S+]([O-])CC[C@@H](N)C(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRIK1 P39086 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46
GRIK3 Q13003 1/20 0.46
GRIN2B Q13224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methionine Sulfoxide SCHEMBL38627 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL14448373 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL995666 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL689456 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL38626 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL689512 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL4418369 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL22076611 0.98 GSR (0.45) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL28993578 0.96 GGT1 (0.44) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL16176754 0.94 GSR (0.42) GSRGRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637420-B2 Method for separation of methionine sulfoxide diastereomers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-26 US claimed
US-20220064216-A1 PEPTIDES AND MEDICAL USES THEREOF ANBITION S.R.L. (IT) 2022-03-03 US claimed
US-20220054583-A1 PEPTIDES AND MEDICAL USES THEREOF ANBITION S.R.L. (IT) 2022-02-24 US claimed
EP-3849582-A1 PEPTIDES AND MEDICAL USES THEREOF Anbition S.r.l. (IT) 2021-07-21 EP claimed
EP-3849583-A1 PEPTIDES AND MEDICAL USES THEREOF Anbition S.r.l. (IT) 2021-07-21 EP claimed
CN-113015539-A Peptides and medical uses thereof 安必圣有限责任公司 2021-06-22 CN claimed
CN-112996528-A Peptides and medical uses thereof 安必圣有限责任公司 2021-06-18 CN claimed
WO-2020053773-A1 PEPTIDES AND MEDICAL USES THEREOF ANBITION S.R.L. (IT) 2020-03-19 WO claimed
WO-2020053772-A1 PEPTIDES AND MEDICAL USES THEREOF ANBITION S.R.L. (IT) 2020-03-19 WO claimed
US-9695191-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2017-07-04 US claimed
EP-2036918-A1 PEPTIDE DERIVATIVE Vexon, Inc. (JP) 2009-03-18 EP claimed
US-20080009448-A1 Peptide Derivative VEXON, INC. (50%) (JP) 2008-01-10 US claimed
EP-0850950-A1 PEPTIDE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-07-01 EP claimed
US-4337247-A ANALGESICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-06-29 US claimed
EP-0005248-B1 TETRAPEPTIDEHYDRAZIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION Takeda Chemical Industries, Ltd. (JP) 1982-03-24 EP claimed
EP-0031567-A2 Tetrapeptidesemicarbazide derivatives and their production and use Takeda Chemical Industries, Ltd. (JP) 1981-07-08 EP claimed
US-4277394-A ANALGESICS, ANTIDIARRHEA, TREATMENT OF MENTAL DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1981-07-07 US claimed
US-4199568-A Tetrapeptide amides RECKITT & COLMAN PRODUCTS LIMITED (GB) 1980-04-22 US claimed
US-4178371-A ANALGESIC, NARCOTIC ANTAGONIST OR ANTIDIARRHEAL AGENT RECKITT & COLMAN PRODUCTS LIMITED (GB) 1979-12-11 US claimed
EP-0005248-A2 Tetrapeptidehydrazide derivatives and process for their preparation Takeda Chemical Industries, Ltd. (JP) 1979-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064216-A1 PEPTIDES AND MEDICAL USES THEREOF FLT1, FLT4, TEK GSR 4206/4885GRM8 4331/4885GRM6 4353/4885
US-20220054583-A1 PEPTIDES AND MEDICAL USES THEREOF FLT1, FLT4, TEK GSR 4206/4885GRM8 4331/4885GRM6 4353/4885
US-20080009448-A1 Peptide Derivative ARGLU1, NGLY1, NPR3 GSR 4547/4885GRM8 2265/4885GRM6 2710/4885
US-12637420-B2 Method for separation of methionine sulfoxide diastereomers MET, MGMT, MAT2B GSR 40/4885GRM8 1743/4885GRM6 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.