Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964040 | 0.85 | FOLH1 (0.66) | MEP1BMRGPRX4FOLH1MEP1A | |
| SCHEMBL40393 | 0.85 | FOLH1 (0.66) | MEP1BMRGPRX4FOLH1MEP1A | |
| SCHEMBL60691 | 0.85 | GSK3B (0.62) | GSK3BMRGPRX4 | |
| SCHEMBL29441888 | 0.85 | GSK3B (0.62) | GSK3BMRGPRX4 | |
| Hydrochloric Acid SCHEMBL8958849 | 0.84 | MRGPRX4 (0.53) | GSK3BMEP1BMRGPRX4FOLH1VNN1 | |
| Hydrochloric Acid SCHEMBL2031438 | 0.84 | GSK3B (0.61) | GSK3BMRGPRX4 | |
| SCHEMBL11706688 | 0.84 | GSK3B (0.61) | GSK3BMRGPRX4 | |
| SCHEMBL27804665 | 0.84 | GSK3B (0.61) | GSK3BMRGPRX4 | |
| SCHEMBL27820119 | 0.84 | GSK3B (0.61) | GSK3BMRGPRX4 | |
| SCHEMBL4030533 | 0.83 | GSK3B (0.54) | GSK3BMEP1BMRGPRX4FOLH1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |