Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552577 | 0.84 | ADRA2C (0.45) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| Hydrochloric Acid SCHEMBL4691512 | 0.81 | KMT2A (0.52) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL27854900 | 0.80 | ADRA2C (0.45) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL17465583 | 0.80 | TDP1 (0.44) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL30802089 | 0.79 | DPP4 (0.52) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL4078551 | 0.79 | AOC3 (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL30436892 | 0.79 | AOC3 (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL12573496 | 0.79 | AOC3 (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL6895263 | 0.77 | KDM4E (0.43) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL6894924 | 0.77 | KDM4E (0.43) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |