Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890913 | 0.86 | HDAC3 (0.39) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL6890916 | 0.86 | HDAC3 (0.39) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL6893539 | 0.79 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1MAPTHDAC1 | |
| SCHEMBL6896032 | 0.79 | KMT2A (0.35) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL6897134 | 0.74 | CA1 (0.39) | KMT2AMEN1LMNANPC1SMN1; SMN2 | |
| SCHEMBL6896021 | 0.73 | MEN1 (0.33) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL6895016 | 0.73 | L3MBTL1 (0.36) | ALDH1A1KMT2AMEN1MAPTHDAC1 | |
| SCHEMBL7118650 | 0.73 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1MAPTHDAC1 | |
| SCHEMBL6624714 | 0.72 | DPP8 (0.38) | ALDH1A1KMT2AMEN1MAPTHDAC3 | |
| SCHEMBL5231403 | 0.72 | PRCP (0.37) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |