Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896027 | 0.79 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL6893539 | 0.78 | L3MBTL1 (0.37) | KMT2AMEN1ALDH1A1L3MBTL1GAA | |
| SCHEMBL6896021 | 0.77 | MEN1 (0.33) | KMT2AMEN1ALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL6890916 | 0.75 | HDAC3 (0.39) | KMT2AMEN1ALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL6890913 | 0.75 | HDAC3 (0.39) | KMT2AMEN1ALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL6897134 | 0.74 | CA1 (0.39) | KMT2AMEN1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL6895016 | 0.72 | L3MBTL1 (0.36) | KMT2AMEN1ALDH1A1L3MBTL1GAA | |
| SCHEMBL7629783 | 0.72 | — | — | |
| SCHEMBL7118650 | 0.71 | L3MBTL1 (0.37) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL6624714 | 0.71 | DPP8 (0.38) | KMT2AMEN1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |