Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16835909 | 0.78 | CDC7 (0.37) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL27976818 | 0.77 | CDC7 (0.45) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL30267535 | 0.77 | CDC7 (0.45) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL18940537 | 0.77 | CDC7 (0.45) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL256341 | 0.77 | MAPT (0.50) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL14312995 | 0.77 | CDC7 (0.49) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL6646174 | 0.77 | CDC7 (0.45) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL29497360 | 0.77 | MAPT (0.50) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL10197254 | 0.77 | CDC7 (0.45) | CDC7CDK2SLC22A12RAPGEF4MAPT | |
| SCHEMBL9911122 | 0.73 | P2RX7 (0.43) | CDC7CDK2RAPGEF4CYP19A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257276-A4 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1257276-A1 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001062255-A1 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-30 | — | — | WO | disclosed |