Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896339 | 0.89 | PIK3CA (0.55) | PIK3CAMTOR | |
| SCHEMBL10196541 | 0.86 | PIK3CA (0.70) | PIK3CAMTOR | |
| SCHEMBL10198433 | 0.84 | PIK3CA (0.70) | PIK3CAMTOR | |
| SCHEMBL503221 | 0.83 | PIK3CA (0.77) | PIK3CAMTOR | |
| SCHEMBL10196526 | 0.82 | MTOR (0.68) | PIK3CAMTOR | |
| SCHEMBL10195779 | 0.81 | PIK3CA (0.68) | PIK3CAMTOR | |
| SCHEMBL6895765 | 0.81 | PIK3CA (0.55) | PIK3CAMTOR | |
| SCHEMBL10195811 | 0.81 | PIK3CA (0.66) | PIK3CAMTOR | |
| SCHEMBL10197828 | 0.81 | PIK3CA (0.69) | PIK3CAMTOR | |
| SCHEMBL10195998 | 0.76 | PIK3CA (0.69) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092197-A1 | 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |