Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892609 | 0.93 | SIGMAR1 (0.65) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6892276 | 0.85 | ALDH1A1 (0.58) | SIGMAR1L3MBTL1HPGD | |
| SCHEMBL4254894 | 0.80 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL10395208 | 0.80 | SIGMAR1 (0.73) | SIGMAR1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL28145268 | 0.78 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL14612322 | 0.78 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL2538905 | 0.78 | SIGMAR1 (0.95) | SIGMAR1 | |
| SCHEMBL696112 | 0.76 | ALDH1A1 (0.74) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2095206 | 0.76 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL10709659 | 0.76 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |