Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194146 | 0.93 | MMP2 (0.53) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL27396675 | 0.88 | BACE1 (0.60) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL6774068 | 0.86 | BACE1 (0.67) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL750395 | 0.82 | BACE1 (0.58) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL3837363 | 0.81 | BACE1 (0.54) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL3839373 | 0.80 | BACE1 (0.53) | BACE1POLBMMP2MMP9CTSL | |
| SCHEMBL27568136 | 0.79 | POLB (0.70) | POLBMMP2MMP9CTSLCTSS | |
| SCHEMBL6323453 | 0.79 | MMP2 (0.73) | POLBMMP2MMP9CTSLCTSS | |
| SCHEMBL6323452 | 0.79 | MMP2 (0.73) | POLBMMP2MMP9CTSLCTSS | |
| SCHEMBL29540673 | 0.79 | MMP2 (0.73) | POLBMMP2MMP9CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833366-B1 | Dihydrostilbene alkanoic acid derivatives | PHARMACIA CORPORATION | 2004-12-21 | — | — | US | disclosed |
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |