Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895533 | 0.93 | NAAA (0.55) | NAAADGKAMEN1THRBHTT | |
| SCHEMBL11682923 | 0.90 | NAAA (0.62) | NAAADGKALPAR3LPAR1LPAR2 | |
| Butane SCHEMBL2046235 | 0.88 | NAAA (0.60) | NAAADGKALPAR3LPAR1LPAR2 | |
| Butane SCHEMBL2043815 | 0.88 | NAAA (0.60) | NAAADGKALPAR3LPAR1LPAR2 | |
| Butane SCHEMBL2051226 | 0.88 | NAAA (0.60) | NAAADGKALPAR3LPAR1LPAR2 | |
| SCHEMBL1408929 | 0.82 | ALDH1A1 (0.50) | NAAADGKALPAR3LPAR1LPAR2 | |
| Diethylamine SCHEMBL27831389 | 0.82 | NAAA (0.53) | NAAADGKALPAR3LPAR1LPAR2 | |
| Diethylamine SCHEMBL27831359 | 0.82 | NAAA (0.53) | NAAADGKALPAR3LPAR1LPAR2 | |
| SCHEMBL13412099 | 0.80 | NAAA (0.77) | NAAADGKAMEN1THRBHTT | |
| SCHEMBL11694217 | 0.80 | NAAA (0.77) | NAAADGKAMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6002029-A | Antiviral prodrugs | CHIMERIX, INC. | 1999-12-14 | — | — | US | disclosed |
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | disclosed |