Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | MMP10 | P09238 | 3/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476992 | 0.88 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4930771 | 0.81 | MMP13 (0.79) | MMP13 | |
| SCHEMBL689697 | 0.81 | MMP13 (0.57) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL689160 | 0.79 | MMP13 (0.70) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL690266 | 0.78 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL689410 | 0.78 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL688066 | 0.78 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL688649 | 0.78 | MMP13 (0.72) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL689394 | 0.76 | MMP13 (0.68) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4934683 | 0.75 | MMP13 (0.87) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |