Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.57 |
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | MMP10 | P09238 | 4/20 | 0.55 |
| ▸ | MMP8 | P22894 | 4/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476992 | 0.81 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL689696 | 0.81 | MMP13 (0.61) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4930771 | 0.80 | MMP13 (0.79) | MMP13 | |
| SCHEMBL4932412 | 0.73 | MMP13 (0.77) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4934683 | 0.73 | MMP13 (0.87) | MMP13 | |
| SCHEMBL688369 | 0.73 | MMP13 (1.00) | MMP13MMP2MMP10MMP8MMP3 | |
| SCHEMBL689160 | 0.73 | MMP13 (0.70) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4936684 | 0.72 | MMP13 (0.81) | MMP13MMP2MMP10MMP8MMP3 | |
| SCHEMBL4932669 | 0.72 | MMP13 (0.78) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL4934517 | 0.72 | MMP13 (0.78) | MMP13MMP2MMP10MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |