Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897132 | 1.00 | MEN1 (0.42) | MEN1KMT2ACYP3A4CYP1A2HDAC3 | |
| SCHEMBL160811 | 0.87 | TRPA1 (0.47) | HDAC3TDP1 | |
| SCHEMBL301113 | 0.87 | TRPA1 (0.47) | HDAC3TDP1 | |
| SCHEMBL27642615 | 0.86 | EGFR (0.47) | TDP1 | |
| SCHEMBL866662 | 0.84 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP1A2NPC1 | |
| SCHEMBL2522305 | 0.84 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP1A2NPC1 | |
| SCHEMBL866661 | 0.84 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP1A2NPC1 | |
| SCHEMBL11960056 | 0.84 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP1A2NPC1 | |
| SCHEMBL11959996 | 0.84 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP1A2NPC1 | |
| SCHEMBL11530802 | 0.81 | HRH1 (0.42) | CYP3A4CYP1A2CNR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10391182-B2 | Bifunctional cytotoxic agents | PFIZER INC. (US) | 2019-08-27 | — | — | US | disclosed |
| EP-0861858-B1 | Polymeric surface coatings | BIOCOMPATIBLES UK LTD (GB) | 2004-06-30 | — | — | EP | disclosed |
| US-6395800-B1 | BLEND OF 2-(METHACRYLOYLOXYETHYL)-2*-(TRIMETHYLAMMONIUM)ETHYL PHOSPHATE POLYMER; MEDICAL EQUIPMENT, CATHETERS; BIOCOMPATIBILITY | BIOCOMPATIBLES LIMITED (GB) | 2002-05-28 | — | — | US | disclosed |
| US-6225431-B1 | COATING SURFACE OF MEDICAL DEVICE WITH POLYMER FORMED BY RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS DISPERSED OR DISSOLVED IN A SOLVENT AND THE SOLVENT IS REMOVED TO LEAVE A STABLE COATING ON SURFACE | BIOCOMPATIBLES LIMITED | 2001-05-01 | — | — | US | disclosed |
| US-6150432-A | IMPROVING THE BIOCOMPATIBILITY OF A POLYMER, DISPERSION OF A POLYMER AND INCREASE LUBRICITY BY BLENDING WITH A ZWITTERIONIC POLYMER; A MEDICAL EQUIPMENT WITH REDUCING FIBRINOGEN ABSORPTION, PLATELET ACTIVATION | BIOCOMPATIBLES LIMITED (GB) | 2000-11-21 | — | — | US | disclosed |
| EP-0810239-B1 | Polymeric surface coatings | BIOCOMPATIBLES LTD (GB) | 2000-09-20 | — | — | EP | disclosed |
| EP-0818479-B1 | Polymeric surface coatings | BIOCOMPATIBLES LTD (GB) | 2000-09-13 | — | — | EP | disclosed |
| US-6087462-A | BONDING OF COATINGS TO SURFACES WITH ZWITTWRIONS | BIOCOMPATIBLES LIMITED (GB) | 2000-07-11 | — | — | US | disclosed |
| EP-0593561-B1 | POLYMERIC SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 2000-03-22 | — | — | EP | disclosed |
| EP-0626983-B1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LTD (GB) | 1999-04-14 | — | — | EP | disclosed |
| US-5705583-A | RENDERING SURFACES BIOCOMPATIBLE | BIOCOMPATIBLES LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| EP-0810239-A2 | Polymeric surface coatings | BIOCOMPATIBLES LIMITED (GB) | 1997-12-03 | — | — | EP | disclosed |
| US-5648442-A | ZWITTERIONIC POLYMERS | BIOCOMPATIBLES LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |
| US-5453467-A | Polymers grafted with quaternary ammonium phosphate acrylates1 | BIOCOMPATIBLES LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |
| EP-0626983-A1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994014897-A1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |
| EP-0601041-A1 | POLYMER TREATMENTS | BIOCOMPATIBLES LIMITED (GB) | 1994-06-15 | — | — | EP | disclosed |
| EP-0593561-A1 | POLYMERIC SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993005081-A1 | POLYMER TREATMENTS | BIOCOMPATIBLES LTD. (GB) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993001221-A1 | POLYMERIC SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10391182-B2 | Bifunctional cytotoxic agents | PAICS, CYTH3, CYTH2 | MEN1 3380/4885KMT2A 2521/4885CYP3A4 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.