Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894106 | 1.00 | VDR (0.45) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20848316 | 1.00 | VDR (0.45) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6254068 | 0.86 | VDR (0.45) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL17029395 | 0.85 | VDR (0.63) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL25892978 | 0.84 | VDR (0.41) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL22919567 | 0.82 | MEN1 (0.55) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL25891630 | 0.82 | ALDH1A1 (0.47) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL25892952 | 0.81 | MEN1 (0.40) | VDRMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20848288 | 0.81 | MAPT (0.56) | VDRMAPTSMN1; SMN2PGRADORA3 | |
| SCHEMBL9243595 | 0.80 | ALDH1A1 (0.56) | VDRMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61267548-A | — | — | None | — | — | JP | disclosed |
| JP-63107930-A | — | — | None | — | — | JP | disclosed |
| JP-63107930-A | — | — | None | — | — | JP | disclosed |
| JP-63107928-A | — | — | None | — | — | JP | disclosed |
| JP-2096591-A | — | — | None | — | — | JP | disclosed |
| JP-61267550-A | — | — | None | — | — | JP | disclosed |
| EP-1426352-A2 | Intermediates for the sythesis of vitamin D and steroid derivatives | The Trustees of Columbia University in the City of New York (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6399767-B1 | COMPOUND CONTAINING OXIRANE RING | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-06-04 | — | — | US | disclosed |
| EP-0931047-A1 | INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND STEROID DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0931047-A4 | — | — | 1999-07-28 | — | — | EP | disclosed |
| WO-1998009935-A1 | INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND STEROID DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-03-12 | — | — | WO | disclosed |
| EP-0184112-B1 | NOVEL VITAMIN D DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-05-09 | — | — | EP | disclosed |
| JP-H0296591-A | PREGNANE DERIVATIVE AND PRODUCTION THEREOF | KURARAY CO LTD | 1990-04-09 | — | — | JP | disclosed |
| US-4891364-A | MINIMIZED EFFECT ON CALCIUM METABOLISM | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-01-02 | — | — | US | disclosed |
| JP-S63107930-A | DRUG CONTAINING 9,10-SECO-5,7,10(19)-PREGNATRIENE DERIVATIVE AS ACTIVE INGREDIENT | CHUGAI PHARMACEUT CO LTD | 1988-05-12 | — | — | JP | disclosed |
| JP-S63107930-A | DRUG CONTAINING 9,10-SECO-5,7,10(19)-PREGNATRIENE DERIVATIVE AS ACTIVE INGREDIENT | CHUGAI PHARMACEUT CO LTD | 1988-05-12 | — | — | JP | disclosed |
| JP-S63107928-A | DRUG CONTAINING 9,10-SECOPREGNATRIENE DERIVATIVE AS ACTIVE INGREDIENT | CHUGAI PHARMACEUT CO LTD | 1988-05-12 | — | — | JP | disclosed |
| JP-S61267548-A | NOVEL 9,10-SECO-5,7,10(19)-PREGNATRIENE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1986-11-27 | — | — | JP | disclosed |
| JP-S61267550-A | 9,10-SECO-5,7,10(19)-PREGNATRIENE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1986-11-27 | — | — | JP | disclosed |