SCHEMBL6897382

SCHEMBL6897382

COC(OC)(OCc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.49
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SRC P12931 1/20 0.45
ALDH1A1 P00352 3/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
MAOB P27338 2/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
NR4A2 P43354 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A3 Q92570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4168819 0.90 KMT2A (0.53) CES1SLC6A2SLC6A3KMT2ATDP1
SCHEMBL2150284 0.82 CES1 (0.62) CES1TDP1SRCALDH1A1RAB9A
SCHEMBL6880604 0.80 CES1 (0.71) CES1SLC6A2SLC6A3KMT2ATDP1
SCHEMBL10384205 0.79 SLC6A2 (0.50) CES1SLC6A2SLC6A3KMT2ATDP1
SCHEMBL6060765 0.79 KMT2A (0.53) CES1SLC6A2SLC6A3KMT2ATDP1
SCHEMBL10941335 0.78 ELANE (0.46) CES1KMT2ASRCALDH1A1RAB9A
SCHEMBL11344345 0.76 MAOB (0.47) SLC6A2SLC6A3KMT2ATDP1ALDH1A1
SCHEMBL29286422 0.75 CES1 (0.55) CES1TDP1SRCALDH1A1RAB9A
SCHEMBL29286420 0.75 CES1 (0.55) CES1KMT2ATDP1SRCALDH1A1
SCHEMBL10941278 0.74 PPARG (0.53) SLC6A2SLC6A3KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040126575-A1 Pressure-sensitive adhesive sheet, method for producing the same and method for using the same as well as a multi-layer sheet for use in the pressure-sensitive adhesive sheet and method for producing the same NITTO DENKO CORPORATION 2004-07-01 US disclosed