Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893522 | 0.90 | ESR1 (0.40) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL27582753 | 0.89 | SMN1; SMN2 (0.42) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL6890772 | 0.89 | ESR1 (0.39) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL3949257 | 0.86 | ESR1 (0.40) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL27582754 | 0.86 | ESR1 (0.37) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL1625907 | 0.81 | AGTR1 (0.43) | ESR1ESR2TP53MAPTNTRK1 | |
| SCHEMBL1625133 | 0.80 | TP53 (0.49) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL1624258 | 0.79 | TDP1 (0.46) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL27600093 | 0.79 | SMN1; SMN2 (0.42) | ESR1ESR2SMN1; SMN2TP53MAPT | |
| SCHEMBL1625941 | 0.79 | KMT2A (0.49) | SMN1; SMN2TP53MAPTPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710054-B2 | CONTAINING SULFONYLAMINOCARBONYL GROUPS; PROSTAGLANDIN INHIBITORS | PFIZER INC | 2004-03-23 | — | — | US | disclosed |