SCHEMBL6897648

SCHEMBL6897648

CCN(CCCCc1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.61
CHRM2 P08172 1/20 0.61
HTR1A P08908 1/20 0.61
ADRA2A P08913 1/20 0.61
CHRM1 P11229 1/20 0.61
DRD1 P21728 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A4 P31645 1/20 0.61
ADRA1A P35348 1/20 0.61
OPRM1 P35372 1/20 0.61
DRD3 P35462 1/20 0.61
SLC6A3 Q01959 1/20 0.61
SIGMAR1 Q99720 5/20 0.59
TSHR P16473 1/20 0.58
AOC3 Q16853 1/20 0.52
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
CNR2 P34972 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909639 0.96 KCNH2 (0.66) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL7138237 0.88 SIGMAR1 (0.62) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL10453658 0.88 TSHR (0.59) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL10524794 0.86 TSHR (0.64) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL9176797 0.86 TSHR (0.57) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL3390445 0.86 KCNH2 (0.63) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL14174039 0.85 CNR2 (0.67) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL11142653 0.84 TSHR (0.59) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL10526946 0.83 KCNH2 (0.58) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL4481666 0.82 TSHR (0.53) KCNH2CHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed