Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390445 | 0.89 | KCNH2 (0.63) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL8092566 | 0.88 | SIGMAR1 (0.61) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL6897648 | 0.88 | KCNH2 (0.61) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL7825708 | 0.87 | SIGMAR1 (0.53) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL10526946 | 0.86 | KCNH2 (0.58) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL6999585 | 0.85 | SIGMAR1 (0.56) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL7003391 | 0.85 | SIGMAR1 (0.56) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL27886895 | 0.85 | TSHR (0.59) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11726661 | 0.84 | TDP1 (0.48) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| Ammonia Solution, Strong SCHEMBL11312321 | 0.84 | KCNH2 (0.56) | SIGMAR1KCNH2CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069126-B1 | TRIAZOLOPURINE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVES, ADENOSINE A3 RECEPTOR COMPATIBILIZING AGENT, AND ASTHMATIC REMEDY | OTSUKA PHARMA CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |