Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7044926 | 0.95 | NPY1R (0.42) | NPY1R | |
| SCHEMBL6900118 | 0.92 | NPY1R (0.40) | TPSAB1NPY1RCASRMEN1KMT2A | |
| SCHEMBL8528714 | 0.91 | TPSAB1 (0.38) | TPSAB1NPY1RCASRMEN1KMT2A | |
| SCHEMBL8528076 | 0.91 | TPSAB1 (0.39) | TPSAB1NPY1RMEN1KMT2ATDP1 | |
| SCHEMBL6899868 | 0.91 | NPY1R (0.42) | TPSAB1NPY1RMEN1KMT2ATDP1 | |
| SCHEMBL7059809 | 0.91 | NPY1R (0.42) | TPSAB1NPY1RMEN1KMT2ATDP1 | |
| SCHEMBL8526447 | 0.90 | TPSAB1 (0.37) | TPSAB1NPY1RCASRMEN1KMT2A | |
| SCHEMBL7750546 | 0.90 | F7 (0.38) | CASRMEN1KMT2ATDP1 | |
| SCHEMBL8526278 | 0.89 | NPY1R (0.39) | TPSAB1NPY1RMEN1KMT2ATDP1 | |
| SCHEMBL30905434 | 0.88 | CNR1 (0.41) | TPSAB1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| US-20040029953-A1 | Use of neuropeptide-y antagonists in treatment of alcoholism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-02-12 | — | — | US | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |