SCHEMBL8770263

SCHEMBL8770263

C=CC[SiH](CC)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
ALDH1A1 P00352 1/20 0.39
SLC22A1 O15245 2/20 0.31
SLC22A2 O15244 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437976 0.91 TSHR (0.44) TSHRALDH1A1SMN1; SMN2THRB
SCHEMBL438729 0.91 TSHR (0.44) TSHRALDH1A1SMN1; SMN2THRB
SCHEMBL6897883 0.88 TSHR (0.48) TSHRALDH1A1SMN1; SMN2THRB
SCHEMBL5968559 0.83 TSHR (0.43) TSHRALDH1A1
SCHEMBL6894712 0.83 TSHR (0.43) TSHRALDH1A1
Fluoride SCHEMBL27912823 0.81 TSHR (0.42) TSHRALDH1A1
SCHEMBL5881395 0.77
SCHEMBL58489 0.77 TSHR (0.44) TSHRALDH1A1SLC22A1SLC22A2SMN1; SMN2
SCHEMBL3899839 0.77
SCHEMBL23701168 0.75 TSHR (0.50) TSHRALDH1A1SLC22A1SMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604401-B1 Production of a catalyst component for producing crystalline polymers CHISSO CORP (JP) 1997-09-24 EP disclosed
EP-0395391-B1 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0404519-B1 A process for producing a high-stiffness polypropylene CHISSO CORP (JP) 1996-08-07 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed