Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 14/20 | 0.38 |
| ▸ | NPY4R | P50391 | 14/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.37 |
| ▸ | NPY2R | P49146 | 5/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898666 | 0.91 | CYP2C9 (0.45) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL6898966 | 0.91 | TDP1 (0.36) | NPY1RNPY4RNPY5R | |
| SCHEMBL7059809 | 0.91 | NPY1R (0.42) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL6899868 | 0.91 | NPY1R (0.42) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7043612 | 0.90 | NPY4R (0.35) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL8528025 | 0.89 | NPY4R (0.34) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL7753039 | 0.89 | NPY4R (0.38) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL1593414 | 0.89 | NPY1R (0.42) | NPY1RNPY4RNPY5RNPY2RNPFFR1 | |
| SCHEMBL6900020 | 0.89 | CASR (0.38) | — | |
| SCHEMBL6901717 | 0.87 | EPOR (0.35) | NPY1RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| US-20040029953-A1 | Use of neuropeptide-y antagonists in treatment of alcoholism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-02-12 | — | — | US | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |