Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 13/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036782 | 0.93 | EPOR (0.36) | EPOREPHX2NR1H4NPY1RNPY4R | |
| SCHEMBL6901908 | 0.92 | KMT2A (0.34) | EPORNPY1RNPY4RNPY5RALDH1A1 | |
| SCHEMBL8528025 | 0.89 | NPY4R (0.34) | EPORNPY1RNPY4RNPY5R | |
| SCHEMBL6900020 | 0.89 | CASR (0.38) | ITGB3ITGA2BALDH1A1TSHR | |
| SCHEMBL7043493 | 0.88 | MEN1 (0.35) | EPOREPHX2NR1H4NPY1RNPY4R | |
| SCHEMBL7059809 | 0.88 | NPY1R (0.42) | NPY1RNPY4RNPY5R | |
| SCHEMBL6899868 | 0.88 | NPY1R (0.42) | NPY1RNPY4RNPY5R | |
| SCHEMBL6898240 | 0.87 | NPY1R (0.38) | NPY1RNPY4RNPY5R | |
| SCHEMBL6898966 | 0.86 | TDP1 (0.36) | NPY1RNPY4RNPY5RTSHR | |
| SCHEMBL6898666 | 0.86 | CYP2C9 (0.45) | NPY1RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| US-20040029953-A1 | Use of neuropeptide-y antagonists in treatment of alcoholism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-02-12 | — | — | US | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |