Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888852 | 0.99 | — | — | |
| SCHEMBL2193642 | 0.79 | THRB (0.34) | — | |
| SCHEMBL2192619 | 0.74 | — | — | |
| SCHEMBL2192230 | 0.74 | FOLH1 (0.31) | — | |
| SCHEMBL2195086 | 0.62 | CYP1A2 (0.37) | — | |
| SCHEMBL891262 | 0.61 | FOLH1 (0.39) | — | |
| SCHEMBL18294497 | 0.60 | HTR1D (0.40) | — | |
| SCHEMBL7047896 | 0.59 | — | — | |
| SCHEMBL24065909 | 0.59 | ALDH1A1 (0.48) | — | |
| SCHEMBL24065907 | 0.59 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907625-A4 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIV PITTSBURGH (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0907625-A1 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIVERSITY OF PITTSBURGH (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000376-A1 | FLUOROUS REACTION AND SEPARATION SYSTEMS | UNIVERSITY OF PITTSBURGH (US) | 1998-01-08 | — | — | WO | disclosed |