SCHEMBL6898478

SCHEMBL6898478

Nc1cccc(Oc2ccc(C(=O)c3ccc(C#Cc4ccccc4)cc3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
SRD5A2 P31213 4/20 0.53
PBRM1 Q86U86 1/20 0.50
POLB P06746 1/20 0.49
FFAR1 O14842 3/20 0.47
PARP10 Q53GL7 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TNKS O95271 1/20 0.46
PARP15 Q460N3 1/20 0.46
PARP14 Q460N5 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
PARP2 Q9UGN5 1/20 0.46
AKR1C3 P42330 1/20 0.45
ALOX5 P09917 2/20 0.44
MEN1 O00255 1/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402554 0.97 MAOB (0.57) MAOBSRD5A2PBRM1POLBFFAR1
SCHEMBL8543799 0.89 MAOB (0.68) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL13059383 0.87 SRD5A2 (0.57) SRD5A2POLBFFAR1PARP10TNKS
SCHEMBL8837213 0.87 MAPT (0.56) SRD5A2POLBFFAR1PARP10ALDH1A1
SCHEMBL8962593 0.87 MAOB (0.63) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL29362975 0.87 MAOB (0.63) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL204441 0.87 MAOB (0.63) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL204289 0.87 MAOB (0.63) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL29394233 0.87 MAOB (0.63) MAOBSRD5A2PBRM1POLBPARP10
SCHEMBL9135237 0.87 SRD5A2 (0.68) SRD5A2POLBFFAR1PARP10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808804-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2014-08-19 US disclosed
US-8808804-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2014-08-19 US disclosed
US-20130101742-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY (US) 2013-04-25 US disclosed
US-20130101742-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY (US) 2013-04-25 US disclosed
US-8309663-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2012-11-13 US disclosed
US-8309663-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2012-11-13 US disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 US disclosed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 US disclosed
US-20080300360-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY 2008-12-04 US disclosed
US-20080300360-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY 2008-12-04 US disclosed
EP-1027341-A4 HIGH CHAR YIELD BENZOXAZINES EDISON POLYMER INNOVATION (US) 2000-12-20 EP disclosed
US-6133401-A STABILIZATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2000-10-17 US disclosed
EP-1027341-A1 HIGH CHAR YIELD BENZOXAZINES Edison Polymer Innovation Corporation (US) 2000-08-16 EP disclosed
US-5973144-A MONOMERS, OLIGOMERS AND POLYMERS ARE DESIRABLY MODIFIED BY ADDING PENDANT FUNCTIONAL GROUPS TO PHENOLIC REACTANTS. ADDITIONAL CHEMICAL BONDS INCREASE THE THERMAL STABILITY OF BENZOXAZINE POLYMERS SUCH THAT THEY CAN WITHSTAND HIGHER USE EDISON POLYMER INNOVATION CORPORATION 1999-10-26 US disclosed
US-5910456-A NONCIRCULAR CROSS-SECTION CARBON FIBERS AND MATRIX RESIN HAVING FLEXURAL ELASTIC MODULUS OF 2.7 GPA OR MORE, LOW WATER ABSORPTION, GOOD OPEN-HOLE COMPRESSION STRENGTH UNDER HOT-WET CONDITIONS AFTER CURING; AIRCRAFT STRUCTURAL MATERIALS TORAY INDUSTRIES, INC. (JP) 1999-06-08 US disclosed
WO-1999018092-A1 HIGH CHAR YIELD BENZOXAZINES EDISON POLYMER INNOVATION CORPORATION (US) 1999-04-15 WO disclosed
US-5644022-A ENDCAPPING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMNINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1997-07-01 US disclosed
US-5599993-A USED FOR ENDCAPPING POLYIMIDES WITH EXCELLENT SOLVENT AND CHEMICAL RESISTANCE, HIGH STRENGTH AND MODULUS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1997-02-04 US disclosed
EP-0750004-A1 PREPREGS AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 1996-12-27 EP disclosed
US-5412066-A Adhesives THER UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1995-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS MAOB 2630/4885SRD5A2 2566/4885PBRM1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.