Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.30 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903808 | 1.00 | KDM4E (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL28461929 | 0.79 | ALDH1A1 (0.46) | MAPTFOLH1 | |
| SCHEMBL28461928 | 0.79 | ALDH1A1 (0.46) | MAPTFOLH1 | |
| SCHEMBL8894666 | 0.79 | FOLH1 (0.47) | FOLH1 | |
| SCHEMBL8894663 | 0.79 | FOLH1 (0.47) | FOLH1 | |
| SCHEMBL5397395 | 0.77 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2346068 | 0.73 | SMN1; SMN2 (0.39) | KDM4ESMN1; SMN2ACE | |
| SCHEMBL2346066 | 0.73 | SMN1; SMN2 (0.39) | KDM4ESMN1; SMN2ACE | |
| SCHEMBL21224186 | 0.72 | MEN1 (0.47) | ACEFOLH1 | |
| SCHEMBL900178 | 0.71 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806362-B2 | ADSORPTION, DESORPTION OF TARGETED NUCLEIC ACIDS | PROMEGA CORPORATION | 2004-10-19 | — | — | US | disclosed |
| EP-1179057-B1 | pH DEPENDENT ION EXCHANGE MATRIX AND METHOD OF USE IN THE ISOLATION OF NUCLEIC ACIDS | PROMEGA CORP (US) | 2004-07-21 | — | — | EP | disclosed |
| EP-1179057-A2 | pH DEPENDENT ION EXCHANGE MATRIX AND METHOD OF USE IN THE ISOLATION OF NUCLEIC ACIDS | PROMEGA CORPORATION (US) | 2002-02-13 | — | — | EP | disclosed |
| US-6310199-B1 | BY ADSORBING TO THE TARGET NUCLEIC ACID AT AN ADSORPTION PH AND RELEASING THE TARGET NUCLEIC ACID AT A DESORPTION PH WHICH IS HIGHER THAN THE ADSORPTION PH; MAGNETIC SILIA PARTICLES; GLYCIDYL LIGANDS; AMINO ACID LIGANDS; SPACERS | PROMEGA CORPORATION | 2001-10-30 | — | — | US | disclosed |
| US-20010014650-A1 | pH dependent ion exchange matrix and method of use in the isolation of nucleic acids | PROMEGA CORPORATION (US) | 2001-08-16 | — | — | US | disclosed |
| WO-2000069872-A2 | pH DEPENDENT ION EXCHANGE MATRIX AND METHOD OF USE IN THE ISOLATION OF NUCLEIC ACIDS | PROMEGA CORPORATION (US) | 2000-11-23 | — | — | WO | disclosed |