SCHEMBL900178

SCHEMBL900178

O=C(O)C(CS)NCCNC(CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
MAPT P10636 1/20 0.54
THRB P10828 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
PTGS2 P35354 1/20 0.54
THPO P40225 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ACE P12821 1/20 0.48
FOLH1 Q04609 3/20 0.45
PTGS1 P23219 1/20 0.40
SLC7A11 Q9UPY5 1/20 0.40
GGT1 P19440 1/20 0.39
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ENPEP Q07075 2/20 0.36
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17378062 1.00 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL900182 1.00 KDM4E (0.54) KDM4EMAPTTHRBALOX15NFKB1
Hydrochloric Acid SCHEMBL16993797 0.97 KDM4E (0.52) KDM4EMAPTTHRBALOX15NFKB1
Ethylene SCHEMBL28132201 0.95 KDM4E (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7259702 0.90 KDM4E (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL2774313 0.89 KDM4E (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL17378053 0.89 KDM4E (0.45) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL17377986 0.89 KDM4E (0.55) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL2774315 0.89 KDM4E (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL20259387 0.89 KDM4E (0.45) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986465-B1 SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS MAX PLANCK GESELLSCHAFT (DE) 2026-05-13 EP claimed
EP-4713029-A1 MODIFIED CELL, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING A MODIFIED CELL Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (DE) 2026-03-25 EP claimed
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2026-02-19 US claimed
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2025-07-24 US claimed
EP-4486395-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2025-01-08 EP claimed
WO-2024261219-A1 MODIFIED CELL, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING A MODIFIED CELL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-12-26 WO claimed
EP-4480500-A1 MODIFIED CELL, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING A MODIFIED CELL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-12-25 EP claimed
EP-4452326-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2024-10-30 EP claimed
CN-118541171-A FAP-targeted pharmaceutical products for cancer treatment and diagnosis 原子治疗有限公司 2024-08-23 CN claimed
EP-4351663-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2024-04-17 EP claimed
WO-2003072143-A1 COMPOSITIONS FOR DELIVERY OF THERAPEUTICS AND OTHER MATERIALS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN, LTD. (US) 2003-09-04 WO claimed
EP-1326523-A2 IMAGING OF ENZYMATIC ACTIVITY THE GENERAL HOSPITAL CORPORATION (US) 2003-07-16 EP claimed
EP-0711178-B1 BLOOD POOL IMAGING COMPOSITION AND METHOD OF ITS USE GEN HOSPITAL CORP (US) 2003-05-21 EP claimed
WO-2002032291-A9 IMAGING OF ENZYMATIC ACTIVITY GEN HOSPITAL CORP (US) 2003-04-17 WO claimed
EP-1286704-A2 ETHYLENEDICYSTEINE (EC)-DRUG CONJUGATES Board of Regents, The University of Texas System (US) 2003-03-05 EP claimed
US-20020127629-A1 Imaging of enzymatic activity NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-12 US claimed
WO-2002032291-A2 IMAGING OF ENZYMATIC ACTIVITY THE GENERAL HOSPITAL CORPORATION (US) 2002-04-25 WO claimed
WO-2001091807-A2 ETHYLENEDICYSTEINE (EC)-DRUG CONJUGATES BOARD OF REGENTS (US) 2001-12-06 WO claimed
US-6284220-B1 Noninvasive imaging of nucleic acid vectors THE GENERAL HOSPITAL CORPORATION 2001-09-04 US claimed
US-5605672-A Blood pool imaging composition and method of its use THE GENERAL HOSPITAL CORPORATION (US) 1997-02-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS FAP, ALK, FIBP KDM4E 2871/4885MAPT 3883/4885THRB 427/4885
US-20020127629-A1 Imaging of enzymatic activity MMP1, ENGASE, MMP2 KDM4E 919/4885MAPT 2637/4885THRB 3950/4885
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM TK1, TK2, TMT1A KDM4E 4412/4885MAPT 2314/4885THRB 520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.