Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746812 | 0.85 | HPGDS (0.33) | SSTR3OPRD1HPGDS | |
| SCHEMBL12158445 | 0.77 | AAK1 (0.41) | SSTR3OPRD1 | |
| SCHEMBL5025741 | 0.76 | AAK1 (0.32) | — | |
| SCHEMBL2579965 | 0.73 | PRCP (0.50) | OPRD1HPGDSPRCPOPRM1 | |
| SCHEMBL2957302 | 0.73 | CYP3A4 (0.52) | HPGDSPRCP | |
| SCHEMBL15710882 | 0.72 | AAK1 (0.39) | SSTR3OPRD1 | |
| SCHEMBL1746987 | 0.72 | PRCP (0.39) | SSTR3HPGDSPRCP | |
| SCHEMBL12158426 | 0.71 | AAK1 (0.38) | SSTR3OPRD1 | |
| SCHEMBL12107456 | 0.71 | AAK1 (0.42) | SSTR3OPRD1 | |
| SCHEMBL13180572 | 0.70 | AAK1 (0.36) | SSTR3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049116-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-02-29 | — | — | EP | disclosed |