SCHEMBL1746987

SCHEMBL1746987

O=C(O)N1CCC[C@]1(Cc1ccccc1)c1ncc(-c2ccc(-c3ccc(-c4cnc([C@@H]5CCCN5)[nH]4)cc3)cc2)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRCP P42785 11/20 0.39
SSTR3 P32745 3/20 0.36
HPGDS O60760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1745558 0.80 PRCP (0.37) PRCPSSTR3HPGDS
SCHEMBL15673755 0.80 PRCP (0.37) PRCPSSTR3HPGDS
SCHEMBL15186158 0.74 HPGDS (0.50) SSTR3HPGDS
Acetic Acid SCHEMBL1746327 0.74 PRCP (0.35) PRCPSSTR3HPGDS
Hydrochloric Acid SCHEMBL16242503 0.73 HPGDS (0.49) PRCPSSTR3HPGDS
Hydrochloric Acid SCHEMBL16242502 0.73 HPGDS (0.49) PRCPSSTR3HPGDS
SCHEMBL12160080 0.73 PRCP (0.60) PRCP
SCHEMBL1745776 0.72 PRCP (0.34) PRCPHPGDS
SCHEMBL689892 0.72 NR3C2 (0.36) PRCPSSTR3HPGDS
SCHEMBL4531214 0.72 HPGDS (0.52) SSTR3HPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049522-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2014-05-14 EP claimed
EP-2385048-A1 Hepatitis C virus inhibitors Bristol-Myers Squibb Company (US) 2011-11-09 EP disclosed
US-20110252687-A1 Canting Vertical Fore Grip with Bipod GRIP POD SYSTEMS, LLC 2011-10-20 US disclosed