Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307843 | 1.00 | MEN1 (0.46) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| SCHEMBL5930989 | 0.85 | SLC6A2 (0.40) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| SCHEMBL9463489 | 0.85 | SLC6A2 (0.47) | MAPTCYP2C9OPRM1OPRD1OPRK1 | |
| SCHEMBL9463220 | 0.85 | SLC6A2 (0.43) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| Phenol SCHEMBL11032573 | 0.83 | ALDH1A1 (0.41) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| SCHEMBL9463599 | 0.82 | SLC6A2 (0.48) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8183495 | 0.82 | MEN1 (0.44) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| SCHEMBL6899385 | 0.82 | MEN1 (0.49) | MEN1MAPTCYP2C9KMT2AOPRM1 | |
| SCHEMBL27560047 | 0.82 | MEN1 (0.44) | MEN1MAPTCYP2C9KMT2ASLC6A2 | |
| SCHEMBL6939638 | 0.81 | MEN1 (0.41) | MEN1MAPTCYP2C9KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1502907-A1 | A process for the preparation of (2-hydroxymethyl-phenyl)-phenyl-methanol derivatives | Synteco S.p.A. (IT) | 2005-02-02 | — | — | EP | claimed |
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | Janssen Biopharma, Inc. (US) | 2022-04-26 | — | — | US | disclosed |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | Janssen Biopharma, Inc. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3864020-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen BioPharma, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-108610237-B | Method for synthesizing o-xylene glycol derivative | 复旦大学 | 2021-07-23 | — | — | CN | disclosed |
| EP-1502907-A1 | A process for the preparation of (2-hydroxymethyl-phenyl)-phenyl-methanol derivatives | Synteco S.p.A. (IT) | 2005-02-02 | — | — | EP | disclosed |
| EP-1502907-A1 | A process for the preparation of (2-hydroxymethyl-phenyl)-phenyl-methanol derivatives | Synteco S.p.A. (IT) | 2005-02-02 | — | — | EP | disclosed |
| EP-1502907-A1 | A process for the preparation of (2-hydroxymethyl-phenyl)-phenyl-methanol derivatives | Synteco S.p.A. (IT) | 2005-02-02 | — | — | EP | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |
| US-4018765-A | HETEROCYCLIC | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3985811-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1976-10-12 | — | — | US | disclosed |
| US-3931217-A | ANALGESIC, PSYCHOSTIMULANT | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | ACE, PNP, FEN1 | MEN1 4045/4885MAPT 2999/4885CYP2C9 171/4885 |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | ACE, FEN1, PNP | MEN1 3791/4885MAPT 3026/4885CYP2C9 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.