SCHEMBL6899576

SCHEMBL6899576

CCCCCCCCCCCCCCCCNC(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.50
TSHR P16473 2/20 0.48
ALDH1A1 P00352 2/20 0.48
THRB P10828 1/20 0.44
ADH1B P00325 1/20 0.44
ADH1C P00326 1/20 0.44
ADH1A P07327 1/20 0.44
ADH4 P08319 1/20 0.44
ADH7 P40394 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
FAAH O00519 1/20 0.41
MAPK1 P28482 1/20 0.41
HRH4 Q9H3N8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
PPARA Q07869 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365367 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL183108 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL8417287 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL6899503 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL23945383 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL23696489 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL19038581 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL7770496 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL1026323 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B
SCHEMBL6175347 1.00 EPHX1 (0.50) EPHX1TSHRALDH1A1THRBADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109562094-A Compositions and methods for enhancing antimicrobial agents 希拉匹克斯生物科学有限公司 2019-04-02 CN claimed
CN-107530317-A Combination of cannabinoids and N-acylethanolamines 希拉匹克斯生物科学有限公司 2018-01-02 CN claimed
CN-102977942-B Deicing composition for military jet fuel PLA AIR FORCE OIL MATERIAL RES INST 2014-09-10 CN claimed
CN-102977942-A Deicing composition for military jet fuel PLA AIR FORCE OIL MATERIAL RES INST 2013-03-20 CN claimed
CN-101185034-A Method for fine line resist stripping ATOTECH DEUTSCHLAND GMBH (DE) 2008-05-21 CN claimed
US-11912997-B2 RNAi agents for inhibiting expression of Superoxide Dismutase 1 (SOD1), compositions thereof, and methods of use Arrowhead Pharmaceuticals, Inc. (US) 2024-02-27 US disclosed
US-20240026363-A1 RNAi Agents for Inhibiting Expression of Superoxide Dismutase 1 (SOD1), Compositions Thereof, and Methods of Use SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2024-01-25 US disclosed
CN-110139882-A High cis-1, 4 block copolymers of polybutadiene and polyisoprene 株式会社普利司通 2019-08-16 CN disclosed
CN-109562094-A Compositions and methods for enhancing antimicrobial agents 希拉匹克斯生物科学有限公司 2019-04-02 CN disclosed
CN-109563449-A Use of enzymes, compositions and methods for removing soils 诺维信公司 2019-04-02 CN disclosed
CN-109477042-A Purposes, cleaning compositions and the method for washing of enzyme 诺维信公司 2019-03-15 CN disclosed
CN-109153943-A manganese bleach catalyst particles 诺维信公司 2019-01-04 CN disclosed
EP-1081187-B1 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORP (JP) 2004-02-18 EP disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 US disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed
US-6355710-B1 MIXTURE WITH FILLER AND AMINE SALT BRIDGESTONE CORPORATION (JP) 2002-03-12 US disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 EP disclosed
EP-1081187-A2 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORPORATION (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912997-B2 RNAi agents for inhibiting expression of Superoxide Dismutase 1 (SOD1), compositions thereof, and methods of use SOD1, SOD3, SMN1; SMN2 EPHX1 3343/4885TSHR 4636/4885ALDH1A1 263/4885
US-20240026363-A1 RNAi Agents for Inhibiting Expression of Superoxide Dismutase 1 (SOD1), Compositions Thereof, and Methods of Use SOD1, SOD3, SMN1; SMN2 EPHX1 3351/4885TSHR 4626/4885ALDH1A1 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.