⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902349 | 0.82 | SIGMAR1 (0.30) | — | |
| SCHEMBL1273416 | 0.82 | — | — | |
| SCHEMBL8507032 | 0.80 | — | — | |
| SCHEMBL18912881 | 0.79 | LCK (0.33) | — | |
| SCHEMBL11745581 | 0.79 | LCK (0.33) | — | |
| SCHEMBL29128707 | 0.79 | — | — | |
| SCHEMBL19098561 | 0.76 | LCK (0.37) | — | |
| SCHEMBL7866457 | 0.76 | LCK (0.32) | — | |
| SCHEMBL8343449 | 0.76 | LCK (0.32) | — | |
| SCHEMBL81588 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274561-B1 | SYNERGISTIC MIXTURE OF SILAMINE AND ADRIAMYCIN; SIDE EFFECT REDUCTION | JAPAN SCIENCE & TECHNOLOGY CORP. (JP) | 2001-08-14 | — | — | US | claimed |
| EP-0819432-B1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | JAPAN SCIENCE & TECH CORP (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6274561-B1 | SYNERGISTIC MIXTURE OF SILAMINE AND ADRIAMYCIN; SIDE EFFECT REDUCTION | JAPAN SCIENCE & TECHNOLOGY CORP. (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-0819432-A1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | Japan Science and Technology Corporation (JP) | 1998-01-21 | — | — | EP | disclosed |