Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899647 | 0.82 | — | — | |
| SCHEMBL18158033 | 0.78 | MEN1 (0.38) | SIGMAR1 | |
| SCHEMBL2235928 | 0.78 | MEN1 (0.38) | SIGMAR1 | |
| SCHEMBL7943548 | 0.77 | CYP2C19 (0.32) | — | |
| SCHEMBL10712667 | 0.77 | SLC2A1 (0.31) | — | |
| SCHEMBL13760389 | 0.75 | MEN1 (0.36) | SIGMAR1 | |
| SCHEMBL232247 | 0.74 | MEN1 (0.39) | SIGMAR1 | |
| SCHEMBL15052708 | 0.74 | MEN1 (0.39) | SIGMAR1 | |
| SCHEMBL2502556 | 0.74 | MEN1 (0.41) | — | |
| SCHEMBL2506194 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274561-B1 | SYNERGISTIC MIXTURE OF SILAMINE AND ADRIAMYCIN; SIDE EFFECT REDUCTION | JAPAN SCIENCE & TECHNOLOGY CORP. (JP) | 2001-08-14 | — | — | US | claimed |
| JP-9208470-A | — | — | None | — | — | JP | disclosed |
| EP-0819432-B1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | JAPAN SCIENCE & TECH CORP (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6274561-B1 | SYNERGISTIC MIXTURE OF SILAMINE AND ADRIAMYCIN; SIDE EFFECT REDUCTION | JAPAN SCIENCE & TECHNOLOGY CORP. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-5910485-A | Antitumor agents comprising as the principal compounds containing silicon and nitrogen | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0819432-A1 | ANTITUMOR AGENTS COMPRISING AS THE PRINCIPAL AGENT COMPOUNDS CONTAINING SILICON AND NITROGEN | Japan Science and Technology Corporation (JP) | 1998-01-21 | — | — | EP | disclosed |
| JP-H09208470-A | ANTITUMOR AGENT HAVING SILICON AND NITROGEN-CONTAINING COMPOUND AS PRINCIPAL INGREDIENT | KAGAKU GIJUTSU SHINKO JIGYODAN | 1997-08-12 | — | — | JP | disclosed |