Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179863 | 0.85 | ESR1 (0.35) | ESR1ESR2MAPK1ELANENR1H2 | |
| SCHEMBL8460639 | 0.85 | ESR1 (0.31) | ESR1ESR2MAPK1ELANENR1H2 | |
| SCHEMBL8459888 | 0.82 | MAPK1 (0.31) | MAPK1ELANE | |
| SCHEMBL30307807 | 0.82 | MAPK1 (0.31) | MAPK1ELANE | |
| SCHEMBL179857 | 0.80 | MAPK1 (0.35) | MAPK1NR1H2NR1H3 | |
| SCHEMBL707822 | 0.77 | ESR1 (0.37) | ESR1ESR2MAPK1NR1H2NR1H3 | |
| SCHEMBL179879 | 0.69 | MAPK1 (0.35) | ESR1ESR2MAPK1NR1H2NR1H3 | |
| SCHEMBL179838 | 0.69 | — | — | |
| SCHEMBL587376 | 0.68 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL18405594 | 0.67 | CA4 (0.39) | MAPK1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708046-A | ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY | DOW CORNING CORPORATION (US) | 1998-01-13 | — | — | US | claimed |
| EP-0764703-A2 | Silicone release coating compositions | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-03-26 | — | — | EP | claimed |
| US-6677407-B1 | LOW TEMPERATURE, QUICK SETTING SILICONE RELEASE AGENTS COMPRISING MIXTURES OF POLYSILOXANES, ORGANOSILICON COMPOUNDS, KARSTEDT CATALYSTS AND DILUENTS, USED AS ADHESIVE TAPES OR LABELS | DOW CORNING CORPORATION | 2004-01-13 | — | — | US | disclosed |
| EP-0826732-A2 | Silicone release coating compositions | DOW CORNING CORPORATION (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5708046-A | ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY | DOW CORNING CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0764703-A2 | Silicone release coating compositions | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |