Sugi Predict

Sugi Predict / Compounds / SCHEMBL587376

SCHEMBL587376

SCHEMBL587376

C#C[Si](C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.39
▸ ESR2 Q92731 1/20 0.39
▸ NR1H2 P55055 2/20 0.32
▸ NR1H3 Q13133 2/20 0.32
▸ MAPT P10636 1/20 0.31
▸ LMNA P02545 2/20 0.30
▸ TSHR P16473 2/20 0.30
▸ ALOX12 P18054 1/20 0.30
▸ ACHE P22303 1/20 0.30
▸ USP2 O75604 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ MAOA P21397 1/20 0.30
▸ MAOB P27338 1/20 0.30
▸ PYCR1 P32322 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9444693 0.79 ESR1 (0.39) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL935728 0.79 ESR1 (0.39) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL9732848 0.79 ESR1 (0.39) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL3947297 0.78 ESR1 (0.42) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL8783588 0.77 ACHE (0.38) ACHE
SCHEMBL716493 0.75 PYCR1 (0.34) PYCR1
SCHEMBL8584755 0.75 LMNA (0.38) LMNAPYCR1
SCHEMBL9632223 0.74 ESR1 (0.39) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL17199746 0.73 ESR1 (0.35) ESR1ESR2
SCHEMBL17395327 0.73 TSHR (0.39) TSHRACHECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 — — US claimed
US-20220056167-A1 Functionalized Cyclic Polymers and Methods of Preparing Same NATIONAL SCIENCE FOUNDATION 2022-02-24 — — US claimed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 — — WO claimed
US-12404353-B2 Olefin polymerization catalyst, olefin polymerization catalyst production method, and olefin polymer production method using the olefin polymerization catalyst JAPAN POLYPROPYLENE CORPORATION (JP) 2025-09-02 — — US disclosed
US-20240397815-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2024-11-28 — — US disclosed
CN-115698102-B Attenuated post-metallocene catalysts 陶氏环球技术有限责任公司 2024-11-26 — — CN disclosed
CN-115698105-B Chemical conversion catalyst 陶氏环球技术有限责任公司 2024-11-08 — — CN disclosed
CN-107955052-B Method for alkynylating 16-substituted-17-ketosteroids 晶体制药独资有限公司 2024-07-05 — — CN disclosed
CN-115315451-B Catalyst for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer using catalyst for olefin polymerization 日本聚丙烯株式会社 2023-12-01 — — CN disclosed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 — — US disclosed
WO-2023171788-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR, AND COMPOUND 富士フイルム株式会社 2023-09-14 — — WO disclosed
US-20080269425-A1 Novel Catalyst WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-10-30 — — US disclosed
WO-2008020774-A1 NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-AIKYNES ADAM MICKIEWICZ UNIVERSITY (PL) 2008-02-21 — — WO disclosed
US-20070265255-A1 SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS GEORGETOWN UNIVERSITY 2007-11-15 — — US disclosed
WO-2007124266-A2 ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-01 — — WO disclosed
WO-2007124286-A1 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-01 — — WO disclosed
US-20070249802-A1 ACENE-THIOPHENE COPOLYMERS WITH SILETHYNLY GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2007-10-25 — — US disclosed
US-20070249087-A1 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2007-10-25 — — US disclosed
WO-2005075074-A1 INORGANIC SOLIDS, SUCH AS POROUS AND PARTICULARLY MESOPOROUS INORGANIC SOLIDS, WHICH ARE MODIFIED BY TRANSITION METAL-CHELATING ORGANIC MOLECULES, PREPARATION METHOD THEREOF AND USE OF SAME AS CATALYSTS SAINT-GOBAIN RECHERCHE (FR) 2005-08-18 — — WO disclosed
US-4714481-A Gas separation membrane MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240397815-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND CRY1, PPOX, PIEZO1 ESR1 164/4885ESR2 1838/4885NR1H2 3557/4885
US-20080269425-A1 Novel Catalyst PPOX, PNMT, POLRMT ESR1 2244/4885ESR2 2822/4885NR1H2 2464/4885
US-20070265255-A1 SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS ADH5, ADH1C, ADH1A ESR1 3302/4885ESR2 2701/4885NR1H2 3850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.