Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460639 | 0.85 | ESR1 (0.31) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| SCHEMBL6899798 | 0.85 | ESR1 (0.31) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| SCHEMBL30307807 | 0.82 | MAPK1 (0.31) | MAPK1ELANE | |
| SCHEMBL8459888 | 0.82 | MAPK1 (0.31) | MAPK1ELANE | |
| SCHEMBL179879 | 0.80 | MAPK1 (0.35) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| SCHEMBL705274 | 0.77 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| SCHEMBL15309958 | 0.74 | ESR1 (0.36) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| SCHEMBL8520332 | 0.71 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL3482029 | 0.71 | NR1H2 (0.46) | ESR1ESR2NR1H2NR1H3MAPK1 | |
| Boric Acid SCHEMBL28491321 | 0.70 | NR1H2 (0.39) | ESR1ESR2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708046-A | ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY | DOW CORNING CORPORATION (US) | 1998-01-13 | — | — | US | claimed |
| EP-0764703-A2 | Silicone release coating compositions | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-03-26 | — | — | EP | claimed |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | DOW SILICONES CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| US-12624256-B2 | Silicone pressure sensitive adhesive composition containing a cyanate-functional silane additive and methods for the preparation and use of said composition | DOW SILICONES CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260117090-A1 | SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP | DOW SILICONES CORP (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260117089-A1 | SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP | DOW SILICONES CORP (US) | 2026-04-30 | — | — | US | disclosed |
| EP-3980481-B1 | POLYSILOXANE CONTROLLED RELEASE ADDITIVE, METHOD FOR THE PREPARATION THEREOF, AND RELEASE COATING COMPOSITION | DOW SILICONES CORP (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4716716-A1 | SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP | Dow Silicones Corporation (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-4716712-A1 | SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP | Dow Silicones Corporation (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-4536769-B1 | COMPOSITION FOR PREPARING A RELEASE COATING | DOW SILICONES CORP (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4330340-B1 | HYDROSILYLATION REACTION CURED SILICONE PRESSURE SENSITIVE ADHESIVE, COMPOSITION AND METHOD FOR ITS PREPARATION, AND USE IN FLEXIBLE DISPLAY DEVICE | DOW SILICONES CORP (US) | 2026-02-25 | — | — | EP | disclosed |
| EP-2069829-A2 | OPTICAL DEVICES AND SILICONE COMPOSITIONS AND PROCESSES FABRICATING THE OPTICAL DEVICES | Dow Corning Corporation (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090146175-A1 | THERMAL STABLE TRANSPARENT SILICONE RESIN COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE | DOW CORNING CORPORATION | 2009-06-11 | — | — | US | disclosed |
| EP-1987084-A2 | LIGHT EMITTING DEVICE ENCAPSULATED WITH SILICONES AND CURABLE SILICONE COMPOSITIONS FOR PREPARING THE SILICONES | Dow Corning Corporation (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1973963-A1 | THERMALLY STABLE TRANSPARENT SILICONE RESIN COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE | Dow Corning Corporation (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2008027280-A2 | OPTICAL DEVICES AND SILICONE COMPOSITIONS AND PROCESSES FABRICATING THE OPTICAL DEVICES | DOW CORNING CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007100445-A2 | LIGHT EMITTING DEVICE ENCAPSULATED WITH SILICONES AND CURABLE SILICONE COMPOSITIONS FOR PREPARING THE SILICONES | DOW CORNING CORPORATION (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007086987-A1 | THERMALLY STABLE TRANSPARENT SILICONE RESIN COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE | DOW CORNING CORPORATION (US) | 2007-08-02 | — | — | WO | disclosed |
| EP-0826732-A2 | Silicone release coating compositions | DOW CORNING CORPORATION (US) | 1998-03-04 | — | — | EP | disclosed |
| EP-0764703-A2 | Silicone release coating compositions | Dow Corning Toray Silicone Company Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117089-A1 | SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP | SMC3, SGMS2, SMC2 | ESR1 1383/4885ESR2 2230/4885NR1H2 1547/4885 |
| US-20260117090-A1 | SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP | COG3, COG2, SMC3 | ESR1 2121/4885ESR2 2710/4885NR1H2 1585/4885 |
| US-12624256-B2 | Silicone pressure sensitive adhesive composition containing a cyanate-functional silane additive and methods for the preparation and use of said composition | CDH1, PIEZO1, SRMS | ESR1 525/4885ESR2 1548/4885NR1H2 3900/4885 |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | HAO2, H1-2, HRH2 | ESR1 231/4885ESR2 350/4885NR1H2 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.