Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 19/20 | 0.69 |
| ▸ | F13A1 | P00488 | 17/20 | 0.69 |
| ▸ | TGM1 | P22735 | 17/20 | 0.69 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.54 |
| ▸ | TGM6 | O95932 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901702 | 0.84 | SMN1; SMN2 (0.58) | TGM2F13A1TGM1ENPP2 | |
| SCHEMBL6902596 | 0.83 | TGM2 (0.68) | TGM2F13A1TGM1TGM3 | |
| SCHEMBL1869913 | 0.82 | TGM2 (1.00) | TGM2F13A1TGM1TGM3TGM6 | |
| SCHEMBL6901635 | 0.79 | SMN1; SMN2 (0.52) | TGM2F13A1TGM1ENPP2 | |
| SCHEMBL6902881 | 0.79 | TGM2 (0.69) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL1876047 | 0.79 | TGM2 (1.00) | TGM2F13A1TGM1TGM3 | |
| SCHEMBL1868875 | 0.79 | TGM2 (1.00) | TGM2F13A1TGM1TGM3TGM6 | |
| SCHEMBL1868878 | 0.79 | TGM2 (1.00) | TGM2F13A1TGM1TGM3TGM6 | |
| SCHEMBL1869832 | 0.79 | TGM2 (1.00) | TGM2F13A1TGM1TGM3TGM6 | |
| SCHEMBL14916351 | 0.76 | TGM2 (0.74) | TGM2F13A1TGM1TGM3TGM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |