Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 20/20 | 0.68 |
| ▸ | TGM1 | P22735 | 20/20 | 0.68 |
| ▸ | F13A1 | P00488 | 19/20 | 0.68 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901811 | 0.86 | F13A1 (0.72) | TGM2TGM1F13A1TGM3 | |
| SCHEMBL6901614 | 0.83 | TGM2 (0.48) | TGM2TGM1F13A1 | |
| SCHEMBL6902881 | 0.83 | TGM2 (0.69) | TGM2TGM1F13A1 | |
| SCHEMBL6899994 | 0.83 | TGM2 (0.69) | TGM2TGM1F13A1TGM3 | |
| SCHEMBL1872601 | 0.81 | TGM2 (1.00) | TGM2TGM1F13A1TGM3 | |
| SCHEMBL6901921 | 0.81 | F13A1 (0.52) | TGM2TGM1F13A1TGM3 | |
| SCHEMBL14915062 | 0.80 | TGM2 (0.75) | TGM2TGM1F13A1TGM3 | |
| SCHEMBL6901323 | 0.79 | MEN1 (0.54) | — | |
| SCHEMBL28741717 | 0.79 | MEN1 (0.54) | — | |
| SCHEMBL6902507 | 0.79 | TGM2 (0.65) | TGM2TGM1F13A1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |