Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905074 | 0.87 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL6903356 | 0.86 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL6905073 | 0.85 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL1906733 | 0.81 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL6905033 | 0.80 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL6903370 | 0.80 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL6402341 | 0.80 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14TAS1R3 | |
| SCHEMBL6905617 | 0.79 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6395572 | 0.79 | MAPK14 (0.78) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL6904778 | 0.79 | MAPK14 (0.64) | MAPK13MAPK12MAPK11MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202959-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2004-09-29 | — | — | EP | claimed |