Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892726 | 0.71 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6898766 | 0.71 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL18110066 | 0.71 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL88028 | 0.71 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1 | |
| E968 SCHEMBL31315354 | 0.65 | LMNA (0.47) | LMNAL3MBTL1TDP1ALDH1A1 | |
| Glycerin SCHEMBL4252347 | 0.65 | LMNA (0.64) | LMNAL3MBTL1TDP1ALDH1A1 | |
| E968 SCHEMBL20559013 | 0.65 | LMNA (0.47) | LMNAL3MBTL1TDP1ALDH1A1 | |
| E968 SCHEMBL121807 | 0.65 | — | — | |
| E968 SCHEMBL17062 | 0.65 | — | — | |
| E968 SCHEMBL10427336 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | claimed |