Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18110066 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| SCHEMBL88028 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| SCHEMBL27566223 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| SCHEMBL27747992 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| SCHEMBL28812939 | 0.79 | TDP1 (0.57) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL4314767 | 0.79 | TDP1 (0.57) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL27732540 | 0.79 | TDP1 (0.57) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| E968 SCHEMBL31315354 | 0.78 | LMNA (0.47) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| E968 SCHEMBL20559013 | 0.78 | LMNA (0.47) | LMNAL3MBTL1TDP1KDM4EMMP2 | |
| E968 SCHEMBL29038531 | 0.75 | LMNA (0.44) | LMNAL3MBTL1TDP1KDM4EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | claimed |
| EP-0161519-A2 | Derivatives of glycerophosphocholine and of glycerophosphoethanol amine, their preparation and use | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1985-11-21 | — | — | EP | disclosed |