Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778970 | 0.88 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4780884 | 0.86 | MAPT (0.70) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2255472 | 0.85 | MAPK13 (0.60) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3627660 | 0.84 | MAPT (0.62) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9176722 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4778966 | 0.84 | CDC25B (0.52) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12124929 | 0.84 | RAB9A (0.69) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL16453466 | 0.83 | MEN1 (0.58) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19245018 | 0.82 | CDC25B (0.57) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2258175 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013787-B1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL SCIENT IND RES (IN) | 2017-08-02 | — | — | EP | disclosed |
| EP-3013787-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | Council of Scientific & Industrial Research (IN) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014207761-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | disclosed |
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |
| US-5854236-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1997047624-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |