Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900636 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL7748806 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6901628 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6899202 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6902041 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6901617 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL9661395 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6367297 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL21357404 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL2275936 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967933-B1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-0960148-B1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORP (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0960148-A4 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORP (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0967933-A4 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORP (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0967933-A1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | United States Surgical Corporation (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0960148-A1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | United States Surgical Corporation (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5919893-A | Polyesteramide, its preparation and surgical devices fabricated therefrom | UNITED STATES SURGICAL CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| US-5902875-A | Polyesteramide, its preparation and surgical devices fabricated therefrom | UNITED STATES SURGICAL CORPORATION (US) | 1999-05-11 | — | — | US | disclosed |
| WO-1998032779-A1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORPORATION (US) | 1998-07-30 | — | — | WO | disclosed |
| WO-1998032398-A1 | POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM | UNITED STATES SURGICAL CORPORATION (US) | 1998-07-30 | — | — | WO | disclosed |
| US-5286837-A | Suspending in an amide solvent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| WO-1993015130-A2 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |
| US-5100992-A | Chain extended with a dicarboxylic acid, block and graft polymers, medical applications, drug delivery | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0396429-A2 | Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1990-11-07 | — | — | EP | disclosed |
| US-4826945-A | POLYESTERS, POLYETHERS, POLYURETHANES | YISSUM RESEARCH DEVELOPMENT COMPANY (IL) | 1989-05-02 | — | — | US | disclosed |
| EP-0295055-A2 | Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical articles made therefrom | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4529792-A | Reacting diamine with lactic or glycolic acid; then bischloroformate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0030822-B1 | SYNTHETIC ABSORBABLE SURGICAL DEVICES OF POLYESTER AMIDES AND PROCESS FOR MAKING THEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| US-4343931-A | FILAMENTS, SUTURES, PROSTHETICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| EP-0030822-A2 | Synthetic absorbable surgical devices of polyester amides and process for making them | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |