SCHEMBL6901628

SCHEMBL6901628

O=C(O)CCCCCOCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
LMNA P02545 3/20 0.67
NFKB1 P19838 1/20 0.67
PMP22 Q01453 1/20 0.67
ALDH1A1 P00352 4/20 0.65
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
SLC22A6 Q4U2R8 2/20 0.53
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
FABP4 P15090 2/20 0.52
ALOX15 P16050 2/20 0.52
PTPN1 P18031 2/20 0.52
KMT2A Q03164 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900636 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL7748806 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL6900744 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL6899202 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL6902041 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL6901617 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL9661395 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL6367297 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL21357404 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL2275936 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967933-B1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORP (US) 2004-12-29 EP disclosed
EP-0960148-B1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORP (US) 2003-04-02 EP disclosed
EP-0960148-A4 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORP (US) 2000-03-08 EP disclosed
EP-0967933-A4 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORP (US) 2000-02-23 EP disclosed
EP-0967933-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM United States Surgical Corporation (US) 2000-01-05 EP disclosed
EP-0960148-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM United States Surgical Corporation (US) 1999-12-01 EP disclosed
US-5919893-A Polyesteramide, its preparation and surgical devices fabricated therefrom UNITED STATES SURGICAL CORPORATION (US) 1999-07-06 US disclosed
US-5902875-A Polyesteramide, its preparation and surgical devices fabricated therefrom UNITED STATES SURGICAL CORPORATION (US) 1999-05-11 US disclosed
WO-1998032779-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORPORATION (US) 1998-07-30 WO disclosed
WO-1998032398-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORPORATION (US) 1998-07-30 WO disclosed
US-5286837-A Suspending in an amide solvent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-02-15 US disclosed
WO-1993015130-A2 PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-05 WO disclosed
US-5100992-A Chain extended with a dicarboxylic acid, block and graft polymers, medical applications, drug delivery BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) 1992-03-31 US disclosed
EP-0396429-A2 Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) 1990-11-07 EP disclosed
US-4826945-A POLYESTERS, POLYETHERS, POLYURETHANES YISSUM RESEARCH DEVELOPMENT COMPANY (IL) 1989-05-02 US disclosed
EP-0295055-A2 Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical articles made therefrom BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) 1988-12-14 EP disclosed
US-4529792-A Reacting diamine with lactic or glycolic acid; then bischloroformate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-07-16 US disclosed
EP-0030822-B1 SYNTHETIC ABSORBABLE SURGICAL DEVICES OF POLYESTER AMIDES AND PROCESS FOR MAKING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed
US-4343931-A FILAMENTS, SUTURES, PROSTHETICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-08-10 US disclosed
EP-0030822-A2 Synthetic absorbable surgical devices of polyester amides and process for making them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-06-24 EP disclosed