Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.60 |
| ▸ | CTSK | P43235 | 14/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146369 | 0.82 | CTSS (0.64) | CTSSCTSKCYP3A4AAK1 | |
| SCHEMBL16474367 | 0.76 | CTSS (0.76) | CTSSCTSK | |
| SCHEMBL16474505 | 0.74 | CTSS (0.69) | CTSSCTSK | |
| SCHEMBL2146713 | 0.73 | CTSS (0.78) | CTSSCTSK | |
| SCHEMBL6899617 | 0.73 | CTSS (0.62) | CTSSCTSK | |
| SCHEMBL2146512 | 0.72 | CTSS (0.66) | CTSSCTSK | |
| SCHEMBL3115130 | 0.71 | CTSS (0.66) | CTSSCTSK | |
| SCHEMBL13390261 | 0.70 | CTSS (0.62) | CTSSCTSK | |
| SCHEMBL6901194 | 0.69 | CTSS (0.64) | CTSSCTSK | |
| SCHEMBL2146766 | 0.68 | CTSS (0.65) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086125-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N.V. ORGANON (NL) | 2011-07-21 | — | — | WO | disclosed |