Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.36 |
| ▸ | CTSL | P07711 | 14/20 | 0.36 |
| ▸ | CTSS | P25774 | 10/20 | 0.36 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214787 | 0.81 | CTSK (0.37) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6215050 | 0.79 | CTSK (0.36) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4830428 | 0.78 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6602296 | 0.73 | CTSL (0.32) | CTSKCTSLCTSS | |
| SCHEMBL4770431 | 0.71 | CTSK (0.44) | CTSKCTSSCTSB | |
| SCHEMBL5971472 | 0.71 | — | — | |
| SCHEMBL4763062 | 0.71 | GRN (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4770472 | 0.71 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14345781 | 0.71 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6836936 | 0.71 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231922-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1231922-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034159-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |