Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 10/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898690 | 0.90 | MTOR (0.69) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6901488 | 0.87 | MTOR (0.59) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899968 | 0.79 | MTOR (0.76) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898696 | 0.79 | MTOR (0.57) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898844 | 0.77 | MTOR (0.69) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899131 | 0.76 | PIK3CA (0.65) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913379 | 0.74 | MTOR (1.00) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL30874351 | 0.74 | MTOR (1.00) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913482 | 0.74 | MTOR (0.65) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL7953828 | 0.73 | PIK3CA (0.51) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |