SCHEMBL6901556

SCHEMBL6901556

[O]c1ccccc1Nc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
TDP1 Q9NUW8 6/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
KDM4E B2RXH2 3/20 0.56
GAA P10253 3/20 0.56
GLA P06280 2/20 0.56
RECQL P46063 1/20 0.56
ALDH1A1 P00352 9/20 0.54
LMNA P02545 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2D6 P10635 1/20 0.54
HSD17B10 Q99714 5/20 0.52
ALOX15 P16050 4/20 0.50
MAPK1 P28482 4/20 0.50
CYP3A4 P08684 4/20 0.50
TSHR P16473 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048296 0.82 NPC1 (0.63) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL444976 0.81 MAPT (0.70) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL5085669 0.75 NPC1 (0.73) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL13363917 0.74 MAPT (0.61) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL1081978 0.73 MAPT (0.54) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL5080930 0.73 HSD17B10 (0.65) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL6404861 0.72 MEN1 (1.00) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL29871430 0.72 MAPT (0.58) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL28969955 0.72 MAPT (0.65) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL11969154 0.71 MEN1 (0.56) MAPTTDP1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5445751-A Heat stabilizers that are reaction products of cerium compounds and alkali metal silanolates or organopolysiloxanes with anilinophenoxy or naphthylaminophenoxy groups DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-08-29 US claimed
EP-0613941-A2 Fluorosilicone lubricant compositions Dow Corning Toray Silicone Company, Limited (JP) 1994-09-07 EP claimed
US-4840743-A Liquid organopolysiloxane compositions DOW CORNING, LTD. (GB) 1989-06-20 US claimed
JP-6256787-A None JP disclosed
US-10190009-B2 Ink composition, ink jet recording method using same, and colored material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20160160065-A1 INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-06-09 US disclosed
EP-3015516-A1 INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2016-05-04 EP disclosed
WO-2004111151-A2 SILICONE-BASED PRESSURE-SENSITIVE ADHESIVE AND ADHESIVE TAPE DOW CORNING TORAY CO., LTD. (JP) 2004-12-23 WO disclosed
US-6627714-B2 Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer MARUZEN PETROCHEMICAL CO., LTD. (JP) 2003-09-30 US disclosed
US-20020058767-A1 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-16 US disclosed
EP-1205497-A2 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-15 EP disclosed
US-5445751-A Heat stabilizers that are reaction products of cerium compounds and alkali metal silanolates or organopolysiloxanes with anilinophenoxy or naphthylaminophenoxy groups DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-08-29 US disclosed
JP-H06256787-A FLUOROSILICONE-BASED LUBRICANT TORAY DOW CORNING SILICONE CO LTD 1994-09-13 JP disclosed
EP-0613941-A2 Fluorosilicone lubricant compositions Dow Corning Toray Silicone Company, Limited (JP) 1994-09-07 EP disclosed
EP-0396971-B1 Stabilized polydiorganosiloxanes and their use in hydraulic applications BAYER AG (DE) 1994-06-08 EP disclosed
US-5013858-A Stablized polyorganosiloxanes and their use as a power transmission medium BAYER AKTIENGESELLSCHAFT (DE) 1991-05-07 US disclosed
EP-0396971-A2 Stabilized polydiorganosiloxanes and their use in hydraulic applications BAYER AG (DE) 1990-11-14 EP disclosed
US-4840743-A Liquid organopolysiloxane compositions DOW CORNING, LTD. (GB) 1989-06-20 US disclosed
US-4840743-A Liquid organopolysiloxane compositions DOW CORNING, LTD. (GB) 1989-06-20 US disclosed
US-4525205-A PRE- AND POSTEMERGENCE; WEED CONTROL ZOECON CORPORATION (US) 1985-06-25 US disclosed