Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.68 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | PLG | P00747 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tranexamic Acid SCHEMBL15902803 | 0.91 | LMNA (0.67) | LMNAKMT2AALDH1A1THRBPLG | |
| Tranexamic Acid SCHEMBL1404323 | 0.91 | LMNA (0.67) | LMNAKMT2AALDH1A1THRBPLG | |
| Tranexamic Acid SCHEMBL675990 | 0.91 | LMNA (0.67) | LMNAKMT2AALDH1A1THRBPLG | |
| SCHEMBL28132953 | 0.89 | TSHR (0.60) | LMNAKMT2AALDH1A1THRBPLG | |
| Sebacic Acid SCHEMBL8982028 | 0.89 | TSHR (0.60) | LMNAKMT2AALDH1A1THRBPLG | |
| SCHEMBL9456678 | 0.89 | LMNA (0.60) | LMNAKMT2AALDH1A1THRBPLG | |
| SCHEMBL7055722 | 0.89 | LMNA (0.60) | LMNAKMT2AALDH1A1THRBPLG | |
| Cyclopropane Carboxylic Acid SCHEMBL28229299 | 0.86 | TSHR (0.50) | LMNAKMT2AALDH1A1THRBPLG | |
| Adipic Acid SCHEMBL6906936 | 0.85 | LMNA (0.59) | LMNAKMT2AALDH1A1THRBPLG | |
| SCHEMBL4524913 | 0.82 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790280-B1 | THERMOPLASTIC RESIN COMPOSITION, INJECTION MOLDING METHOD THEREOF AND INJECTION MOLDED ARTICLE | POLYPLASTICS CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6010760-A | BLENDING THERMOPLASTIC RESIN AND LIQUID CRYSTALLINE POLYMER; FORMING ANISOTROPIC MELT; KNEADING | POLYPLASTICS CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0790280-A1 | THERMOPLASTIC RESIN COMPOSITION, INJECTION MOLDING METHOD THEREOF AND INJECTION MOLDED ARTICLE | POLYPLASTICS CO. LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |