Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5641590 | 0.81 | CA2 (0.32) | CA2 | |
| SCHEMBL7162294 | 0.80 | CA2 (0.34) | CA2GABRA1GABRB2RXRARXRB | |
| SCHEMBL5871260 | 0.78 | CA2 (0.31) | CA2 | |
| SCHEMBL5644353 | 0.78 | CA2 (0.36) | CA2GABRA1GABRB2RXRARXRB | |
| SCHEMBL5871943 | 0.76 | ALOX12 (0.33) | CA2RXRARXRBRXRG | |
| SCHEMBL5871097 | 0.76 | ALOX12 (0.33) | CA2 | |
| SCHEMBL5871242 | 0.75 | CA2 (0.34) | CA2GABRA1GABRB2RXRARXRB | |
| SCHEMBL29183341 | 0.74 | — | — | |
| SCHEMBL9156184 | 0.74 | CA2 (0.36) | CA2GABRA1GABRB2RXRARXRB | |
| SCHEMBL4606175 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677333-B1 | ANTIISCHEMIC AGENTS; BRAIN, CARDIOVASCULAR, MUSCULAR, AND GASTROINTESTINAL DISORDERS; ANALGESICS, ANTIDIABETIC AGENTS; RETROVIRUS SENSITIZERS; ALZHEIMER*S DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1148053-A1 | 2H-PHTHALAZIN-1-ONE DERIVATIVES AND DRUGS COMPRISING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |